Chiara Paganini Selected Research

Diastrophic dysplasia

1/2021	Improvement of the skeletal phenotype in a mouse model of diastrophic dysplasia after postnatal treatment with N-acetylcysteine.
12/2017	Polyethylene Glycol-Poly-Lactide-co-Glycolide Block Copolymer-Based Nanoparticles as a Potential Tool for Off-Label Use of N-Acetylcysteine in the Treatment of Diastrophic Dysplasia.
10/2015	N-acetylcysteine treatment ameliorates the skeletal phenotype of a mouse model of diastrophic dysplasia.

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Chiara Paganini Research Topics

Disease

3	Diastrophic dysplasia 01/2021 - 10/2015
2	Desbuquois syndrome 08/2021 - 01/2019
2	Mucopolysaccharidosis VI (Syndrome, Maroteaux-Lamy) 01/2020 - 12/2018
1	Intellectual Disability (Idiocy) 10/2022
1	Body Weight (Weight, Body) 01/2021
1	Disease Progression 04/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2019
1	Menstruation Disturbances 01/2018
1	Bulimia (Binge Eating) 01/2018
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 01/2018
1	Gerodermia osteodysplastica 01/2018
1	Weight Gain 01/2018
1	Congenital Abnormalities (Deformity) 10/2015

Drug/Important Bio-Agent (IBA)

3	GlycosaminoglycansIBA 08/2021 - 12/2018
3	Acetylcysteine (Siran)FDA LinkGeneric 01/2021 - 10/2015
2	Proteoglycans (Proteoglycan)IBA 10/2022 - 01/2018
2	ChloridesIBA 01/2021 - 10/2015
2	Sulfates (Sulfates, Inorganic)IBA 01/2021 - 10/2015
2	N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B)IBA 01/2020 - 12/2018
2	EnzymesIBA 01/2020 - 12/2018
1	Proteins (Proteins, Gene)FDA Link 10/2022
1	Tumor Viral Antigens (Large T Antigen)IBA 08/2021
1	nucleotidaseIBA 01/2019
1	GlycosyltransferasesIBA 01/2019
1	Uridine Diphosphate (UDP)IBA 01/2019
1	SulfotransferasesIBA 01/2019
1	CalciumIBA 01/2019
1	Insulin (Novolin)FDA Link 01/2018
1	AndrogensIBA 01/2018
1	polyethylene glycol-poly(lactide-co-glycolide)IBA 12/2017
1	Sulfhydryl Compounds (Thiols)IBA 10/2015
1	AntiportersIBA 10/2015

Therapy/Procedure

1	Injections 01/2021
1	Therapeutics 04/2020
1	Off-Label Use 12/2017